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Two new open-source tools are making fluorescence lifetime imaging microscopy (FLIM) faster, more accessible, and better suited to live imaging research. Developed by Ph.D. student Sofia Kapsiani in Professor Gabi Kaminski Schierle’s Molecular Neuroscience Group at...
Enhancer sequences in DNA help regulate gene expression. In cancer, these can be rewired to promote expression of oncogenes. Although the human genome is three billion base pairs long, its 3D folding within the nucleus plays a crucial role in regulating gene...
Cells use small extracellular vesicles (sEVs) to transfer cargo and chemical messengers to neighboring and distant cells. Ryosuke Kojima, a synthetic and chemical biologist at the University of Tokyo, previously explored sEVs as delivery vehicles for therapeutic...
High-grade serous carcinoma cells. A new study explains the genetic underpinnings of a rare and aggressive form of ovarian cancer and offers a potential pathway for new treatments. High-grade serous carcinoma, the most common type of ovarian cancer, usually begins in...
Macrophages engulf bacteria and turn them into nutrients to fuel themselves. An article published by The Scientist highlights a recent study in Nature that explores how macrophages, the immune cells that engulf bacteria, can use nutrients from these microbes to...
An example of 3D modeling generated by new AI tool. In a leap forward for genetic and biomedical research, two scientists at the University of Missouri have developed a powerful new artificial intelligence tool that can predict the 3D shape of chromosomes inside...
Overview of SAVANA. Long-read sequencing technologies analyse long, continuous stretches of DNA. These methods have the potential to improve researchers' ability to detect complex genetic alterations in cancer genomes. However, the complex structure of cancer genomes...
A team of researchers led by professors Wybren Jan Buma at the University of Amsterdam and Vasilios Stavros at the University of Warwick (U.K.) have laid the groundwork for using urocanic acid and its derivatives as a novel class of sunscreen filters. Urocanic acid is...
The images show the abdomen of flies in which a specific enhancer region has been modified. Depending on how much and which part of the region is modified, different areas of the pigment pattern change. This shows that the region contains several non-modular enhancers...
Tucked away on the kitchen countertop sits a bubbling, living goop in a jar. Each day, a mixture of flour and water feeds the beige concoction, commencing a ritualistic dance that summons wild yeast and bacteria from the air. This transformation turns simple...















