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A Master Regulator of Gene Expression

T cells are the cornerstone of CAR T cell therapy. By enhancing the activity of these cells, researchers can boost their efficacy in eliminating cancer cells. Researchers used a CRISPR-based platform to identify master regulators of T cell function. ELLA MARU STUDIO...

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How a natural compound from sea squirts combats cancer

Trabectedin, an anti-cancer drug originally isolated from the sea squirt Ecteinascidia turbitana, is known to form cytotoxic DNA adducts. It is used to treat sarcomas and ovarian cancers and, in contrast to most antitumor agents, exerts its full activity in cells with...

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Optimizing Gene Editing with PARP1 CRISPR Plasmids

PARP1 CRISPR Plasmids provide researchers with cutting edge tools for refining cell transfection and gene editing protocols. SANTA CRUZ BIOTECHNOLOGY, INC Gene editing is revolutionizing the understanding of health and disease, providing researchers with vast...

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