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Whole slide image illustrating the detection of key histological structures such as glands and cells. A recent study from the University of Warwick,...

Researchers develop a CRISPR tool that directly edits and screens genes in primary acute myeloid leukaemia cells from patients. Scientists from Penn...

Structure and specificity of the colibactin-DNA interstrand cross-link. Colibactin is a potent and highly unstable toxin produced by certain strains...

Enhancing the base mismatch sensitivity and specificity of FnCas9 through protein engineering. Liquid biopsy is becoming increasingly valuable for...

Scientists at UCL and Great Ormond Street Hospital (GOSH) have developed a world-first gene therapy, BE-CAR7, using base-edited immune cells to...

Scientists at the University of South Australia have developed an AI-powered method that reveals how groups of genes work together to drive cancer...

Dysfunction in the movement of RNA polymerase II (Pol II), the enzyme that transcribes DNA into RNA, has been linked to cancer and aging....

A translation-control strategy based on DNA–mRNA hybrids. The damaged base (in red) is removed by a repair enzyme, after which the DNA and mRNA...

Graphical abstract. Yale researchers David Breslow and Mustafa Khokha have developed a novel  CRISPR screening technology that provides...

Researchers from the Turku Bioscience Center at the University of Turku, Finland, including Professor Laura Elo's Computational Biomedicine research...

Snapshots from all-atom MD simulations tentatively indicate that non-specific interactions of the polyadenine oligos with the SiNx surfaces are...

Structural comparison of AAC(3)-Ia, AAC(3)-XIa, and AAC(3)-IIIa. The global battle against antibiotic-resistant superbugs has become more...