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Scientists at UCL and Great Ormond Street Hospital (GOSH) have developed a world-first gene therapy, BE-CAR7, using base-edited immune cells to...

Scientists at the University of South Australia have developed an AI-powered method that reveals how groups of genes work together to drive cancer...

Dysfunction in the movement of RNA polymerase II (Pol II), the enzyme that transcribes DNA into RNA, has been linked to cancer and aging....

A translation-control strategy based on DNA–mRNA hybrids. The damaged base (in red) is removed by a repair enzyme, after which the DNA and mRNA...

Graphical abstract. Yale researchers David Breslow and Mustafa Khokha have developed a novel  CRISPR screening technology that provides...

Researchers from the Turku Bioscience Center at the University of Turku, Finland, including Professor Laura Elo's Computational Biomedicine research...

Snapshots from all-atom MD simulations tentatively indicate that non-specific interactions of the polyadenine oligos with the SiNx surfaces are...

Structural comparison of AAC(3)-Ia, AAC(3)-XIa, and AAC(3)-IIIa. The global battle against antibiotic-resistant superbugs has become more...

Images draw a comparison between the simulated folding and experimentally determined structures of RNA stem loops. A new study led by Associate...

Structural variants detected by GPM. Traditional genetic tests analyse DNA in a one-dimensional way, often missing crucial, disease-causing...

The aminoglycoside-modifying enzyme Eis2 activates FF-NH2. Scientists at St. Jude Children's Research Hospital have developed a strategy that turns...

To accelerate the discovery of new antibiotics, microbiologist Cesar de la Fuente develops computational tools to look for (“encrypted”)...